About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:166841 Nordstrand LM, et al., Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. PLoS One. 2010;5(11):e13827
Assay type: RNA in situ
MGI Accession ID: MGI:5805972
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: Bmp2 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 8A wild type: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: fronto-nasal process Present 8A Bmp2 Wild type
TS19: hindlimb bud Present Regionally restricted 8A Bmp2 Wild type , 8B Bmp2 Wild type Expression was detected in a posterior domain.
TS19: handplate apical ectodermal ridge Present 8A Bmp2 Wild type , 8B Bmp2 Wild type
Specimen 8A Alkbh1-/-: embryonic day 11.5; Alkbh1tm1Klng/Alkbh1tm1Klng (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 8A Bmp2 Alkbh1-/- Expression was induced in the lateral telencephalon of the mutant.
TS19: fronto-nasal process Present 8A Bmp2 Alkbh1-/- Expression was increased in the mutant.
TS19: 2nd branchial arch mesenchyme Present Widespread 8A Bmp2 Alkbh1-/- Expression was upregulated.
TS19: mandibular process mesenchyme Present Widespread 8A Bmp2 Alkbh1-/- Expression was upregulated.
TS19: maxillary process mesenchyme Present Widespread 8A Bmp2 Alkbh1-/- Expression was upregulated.
TS19: hindlimb bud Ambiguous 8A Bmp2 Alkbh1-/- , 8B Bmp2 Alkbh1-/- Expression disappeared from the posterior domain in the hindlimb.
TS19: forelimb bud mesenchyme Present 8B Bmp2 Alkbh1-/- , 8A Bmp2 Alkbh1-/- Expression in the apical ectodermal ridge of the forelimb diffused proximally into the mesenchyme.
TS19: handplate apical ectodermal ridge Present 8B Bmp2 Alkbh1-/- , 8A Bmp2 Alkbh1-/- Expression in the apical ectodermal ridge of the forelimb diffused proximally into the mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory