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Gene Expression Data
Assay Details
Assay
Reference: J:103131 Purcell P, et al., Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction. Gene Expr Patterns. 2005 Dec;6(1):110-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5910090
Gene symbol: Dach1
Gene name: dachshund family transcription factor 1
Results
Specimen 2E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Strong Regionally restricted 2E Strong expression at dorsal edge of optic vesicle, fated to form future ciliary marginal zone.
TS15: eye surface ectoderm Present Regionally restricted 2E Expression in overlying surface ectoderm.
TS15: eye mesenchyme Present Regionally restricted 2E Expression in peri-ocular mesenchyme.
Specimen 2F: embryonic day 9.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present Regionally restricted 2F Expression maintained in optic vesicle. Expression not higher in the future ciliary marginal zone.
TS15: eye mesenchyme Present Regionally restricted 2F Expression in peri-ocular mesenchyme.
Specimen 2G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: retina epithelium Present Regionally restricted 2G Expression in neuronal and pigmented layer of retina.
TS17: eye mesenchyme Present Regionally restricted 2G Expression in peri-ocular mesenchyme.
TS17: lens pit Ambiguous 2G Expression down-regulated in lens pit.
Specimen 2H: embryonic day 10.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS17: optic cup Present Regionally restricted 2H Expression persisted in optic vesicle.
TS17: eye mesenchyme Present Regionally restricted 2H Expression persisted in periocular mesenchyme.
Specimen 3C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present Regionally restricted 3C Expression in developing ciliary marginal zone.
TS19: lens vesicle Present 3C
TS19: pigmented retinal epithelium Present 3C
TS19: cornea epithelium Present 3C Expression in surface ectoderm that will form the cornea.
Specimen 3F: embryonic day 11.5; Dach1tm1Mrd/Dach1tm1Mrd (more )
Structure Level Pattern Image Note
TS19: eye Absent 3F Expression reduced to non-specific levels.
Specimen 4C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nose Present Regionally restricted 4C Expression in prospective nasal ectoderm, with similar expression patterns in both nuclei and cytoplasm.
Specimen 4D: embryonic day 9.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS15: nose Present Regionally restricted 4D Expression in prospective nasal ectoderm, with similar expression patterns in both nuclei and cytoplasm.
Specimen 4J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: latero-nasal process mesenchyme Present 4J
TS17: medial-nasal process mesenchyme Present 4J
Specimen 4K: embryonic day 10.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS17: nasal epithelium Absent 4K No expression in prospective nasal ectoderm.
TS17: forebrain Present 4K Authors report that forebrain expression is preserved.
TS17: nasal mesenchyme Present 4K Authors report that forebrain expression is preserved.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory