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Gene Expression Data
Assay Details
Assay
Reference: J:173393 Chung SH, et al., Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum. Neural Dev. 2011;6:25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5912033
Gene symbol: Klc3
Gene name: kinesin light chain 3
Antibody: anti-KLC3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was 4% paraformaldehyde/0.02% glutaraldehyde with a post-fix in 4% paraformaldehyde.
Results
Specimen 5A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum interpositus nucleus Strong 5A
TS28: deep cerebellar nucleus Strong 5A
TS28: dentate nucleus Strong 5A
TS28: fastigial nucleus Strong 5A
TS28: vestibular nucleus Strong 5A
Specimen 5B: postnatal adult; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS28: deep cerebellar nucleus Present Regionally restricted 5B Expression is in the interposed and lateral nuclei but the anterior part of the medial nuclei is missing in this mutant.
TS28: cerebellum interpositus nucleus Present 5B
TS28: dentate nucleus Present 5B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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