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Gene Expression Data
Assay Details
Assay
Reference: J:243789 Chang AH, et al., DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6107849
Gene symbol: Cxcl12
Gene name: C-X-C motif chemokine ligand 12
Reporter: RFP
Direct Detection
Results
Specimen 5C upper: embryonic day 16.5; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Structure Level Pattern Image Note
TS24: coronary artery Strong 5C upper merge , 5C upper Cxcl12 Expressed in both the coronary artery and adjacent remodeling zones.
Specimen 5C lower: embryonic day 16.5; Cxcl12tm2.1Sjm/Cxcl12+, Dach1tm1Mrd/Dach1tm1Mrd (more )
Structure Level Pattern Image Note
TS24: coronary artery Present 5C lower Cxcl12 , 5C lower merge Significantly less expression in both the coronary artery and adjacent remodeling zones, compared with the control.
Specimen not shown: postnatal; Cxcl12tm2.1Sjm/Cxcl12+ (more )
Structure Level Pattern Image Note
TS28: coronary artery Present
Specimen not shown: postnatal; Cxcl12tm2.1Sjm/Cxcl12+, Dach1tm1Mrd/Dach1tm1Mrd (more )
Structure Level Pattern Image Note
TS28: coronary artery Present Expression was down-regulated specifically in large arteries, compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory