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Gene Expression Data
Assay Details
Assay
Reference: J:243789 Chang AH, et al., DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324
Assay type: RNA in situ
MGI Accession ID: MGI:6107850
Gene symbol: Cxcl12
Gene name: C-X-C motif chemokine ligand 12
Probe: Cxcl12 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5E Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: coronary artery Present 5E upper Expressed in endothelial cells.
TS24: heart Present 5E upper

Specimen 5E eCKO: embryonic day 16.5; Dach1tm1c(KOMP)Wtsi/Dach1tm1c(KOMP)Wtsi, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: coronary artery Present 5E lower Decreased endothelial expression, compared with the control.
TS24: heart Present 5E lower


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory