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Gene Expression Data
Assay Details
Assay
Reference: J:87368 Raetzman LT, et al., Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol. 2004 Jan 15;265(2):329-40
Assay type: RNA in situ
MGI Accession ID: MGI:6117450
Gene symbol: Dll1
Gene name: delta like canonical Notch ligand 1
Probe: Dll1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis Present Widespread 1K Expression throughout the entire prospective intermediate lobe.
TS20: adenohypophysis pars anterior Present Widespread 1K Authors report expression in most progenitor cells at 12.5 dpc.

Specimen 1L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars intermedia Present Widespread 1L Expression throughout the presumptive intermediate lobe extending to the margin.
TS22: remnant of Rathke's pouch Present Regionally restricted 1L Expression restricted to a subset of progenitor cells at with highest expression in peri-luminal progenitor cells.

Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 3C

Specimen 3D: embryonic day 12.5; Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present 3D Expression slightly and consistently elevated in mutant pituitary compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory