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Gene Expression Data
Assay Details
Assay
Reference: J:248338 Teoh JJ, et al., BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain. PLoS One. 2017;12(4):e0175888
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6149057
Gene symbol: Mapt
Gene name: microtubule-associated protein tau
Antibody: anti-Tau1
Detection system: Secondary antibody
Results
Specimen 6Avii: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Avii
TS25: thalamus Present 6Avii

Specimen 6Aviii: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Aviii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: thalamus Present 6Aviii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen 6Ax: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Ax
TS25: thalamus Present 6Ax

Specimen 6Axi: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: neocortex Present 6Axi This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: thalamus Present 6Axi This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen 6Axii: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present 6Axii
TS25: neocortex Present 6Axii

Specimen 6Axiii: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: corpus callosum Present 6Axiii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.
TS25: neocortex Present 6Axiii This mutant shows defects in axonal projection, axonal pathfinding, and axonal extension.

Specimen S3A ctrl left: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl left Tau-1

Specimen S3A ctrl middle: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl middle Tau-1

Specimen S3A ctrl right: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present S3A ctrl right Tau-1

Specimen S3A geo/geo left: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo left Tau-1 Expression in this mutant is the same as in wild-type.

Specimen S3A geo/geo middle: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo middle Tau-1 Expression in this mutant is the same as in wild-type.

Specimen S3A geo/geo right: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS23: brain Present S3A geo/geo right Tau-1 Expression in this mutant is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory