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Gene Expression Data
Assay Details
Assay
Reference: J:134595 Anthony TE, et al., The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol. 2007 Jan 10;500(2):368-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6149222
Gene symbol: Mthfd1
Gene name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Antibody: anti-MTHFD1
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural tube Present Ubiquitous 2A
Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 2B
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2C Expression is in both neurons and radial glia.
Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2D Expression is in both neurons and radial glia.
Specimen 2E: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Tubb3 (assay MGI:6149223).
Structure Level Pattern Image Note
TS20: spinal cord Present 2G , 2E Expression is in both neurons and radial glia.
Specimen 2H: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Nes (assay MGI:6149221).
Structure Level Pattern Image Note
TS20: spinal cord Present 2J , 2H
Specimen 2K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present 2K
Specimen 2L: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Tubb3 (assay MGI:6149223).
Structure Level Pattern Image Note
TS20: neocortex Present 2L , 2N
Specimen 2P: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 2P Expression is in neuronal and radial glial cell bodies.
Specimen 2R: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 2R Expression is in neuronal and radial glial cell bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory