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Gene Expression Data
Assay Details
Assay
Reference: J:216216 Agrawal P, et al., Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate. Dev Dyn. 2014 Nov;243(11):1470-6
Assay type: RNA in situ
MGI Accession ID: MGI:6160300
Gene symbol: Epha3
Gene name: Eph receptor A3
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present 1A

Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 2nd branchial arch Present 1D
TS17: 1st branchial arch mandibular component Strong Regionally restricted 1D Highly expressed in the proximal part of the mandibular component of first branchial arch at E10.5 and E11.5.

Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 2nd branchial arch Present 1G
TS19: mandibular process Strong Regionally restricted 1G Highly expressed in the proximal part of the mandibular component of first branchial arch at E10.5 and E11.5.
TS19: maxillary process Absent 1G

Specimen 1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 2nd branchial arch Present 1J
TS19: mandibular process Strong Regionally restricted 1J Highly expressed in the proximal part of the mandibular component of first branchial arch at E10.5 and E11.5.
TS19: maxillary process Absent 1J

Specimen 2A: embryonic day 12.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS20: latero-nasal process Present 2A
TS20: medial-nasal process Absent 2A

Specimen 2D: embryonic day 12.5 (more )
Note: Middle section.
Structure Level Pattern Image Note
TS20: nasal septum Present Regionally restricted 2D Highly expressed in the proximal part of the mandibular component of first branchial arch at E10.5 and E11.5.
TS20: maxillary process Present Regionally restricted 2D Expression in lateral parts of maxillary prominence.
TS20: palatal shelf mesenchyme Present Regionally restricted 2D Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS20: tongue Present Regionally restricted 2D Expression in lateral tongue mesenchyme at all stages examined.

Specimen 2G: embryonic day 12.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Strong Regionally restricted 2G Abundantly expression in lateral aspect of palatal shelves at pre-elevation stages.
TS20: tongue Present Regionally restricted 2G Expression in lateral tongue mesenchyme at all stages examined.

Specimen 3A: embryonic day 13.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS21: nasal septum Present Regionally restricted 3A In anterior sections, restricted pattern of expression in lateral nasal septum.
TS21: maxilla Present Regionally restricted 3A Expression in lateral parts of maxillary prominence.
TS21: palatal shelf mesenchyme Present Regionally restricted 3A Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS21: tongue Present Regionally restricted 3A Expression in lateral tongue mesenchyme at all stages examined.

Specimen 3D: embryonic day 13.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Regionally restricted 3D Expression along the oral side of palatal shelves after elevation occured.
TS21: tongue Present Regionally restricted 3D Expression in lateral tongue mesenchyme at all stages examined.

Specimen 4A: embryonic day 14.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS22: nasal septum Strong Regionally restricted 4A In anterior sections, restricted pattern of expression in lateral nasal septum.
TS22: maxilla Present Regionally restricted 4A Expression in lateral parts of maxillary prominence.
TS22: palatal shelf mesenchyme Present Regionally restricted 4A Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS22: tongue Present Regionally restricted 4A Expression in lateral tongue mesenchyme at all stages examined.

Specimen 4D: embryonic day 14.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present Regionally restricted 4D Expression restricted to palatal mesenchyme lingual to molar tooth buds.
TS22: tongue Present Regionally restricted 4D Expression in lateral tongue mesenchyme at all stages examined.

Specimen 5C: embryonic day 14.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5C Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5C Reduced expression in epithelial cells. Expression not detected at significant levels in the midline epithelia seam.

Specimen 5H: embryonic day 14.5 (more )
Note: Middle section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5H Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5H Reduced expression in epithelial cells. Expression not detected at significant levels in the midline epithelia seam.

Specimen 5M: embryonic day 14.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5M Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5M Reduced expression in epithelial cells. Expression not detected at significant levels in the midline epithelia seam.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory