About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:216216 Agrawal P, et al., Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate. Dev Dyn. 2014 Nov;243(11):1470-6
Assay type: RNA in situ
MGI Accession ID: MGI:6160301
Gene symbol: Epha4
Gene name: Eph receptor A4
Results
Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Ambiguous 1B

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch maxillary component Present 1E
TS17: latero-nasal process Absent 1E

Specimen 1H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxillary process Present 1H
TS19: mandibular process Present 1H

Specimen 1K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxillary process Present 1K
TS19: mandibular process Present 1K

Specimen 2B: embryonic day 12.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS20: latero-nasal process Present 2B
TS20: medial-nasal process Present 2B

Specimen 2E: embryonic day 12.5 (more )
Note: Middle section.
Structure Level Pattern Image Note
TS20: nasal septum Present Regionally restricted 2E
TS20: maxillary process Present Regionally restricted 2E
TS20: palatal shelf mesenchyme Present Regionally restricted 2E Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS20: tongue Present Regionally restricted 2E

Specimen 2H: embryonic day 12.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Present Regionally restricted 2H Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS20: tongue Present Regionally restricted 2H

Specimen 3B: embryonic day 13.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS21: nasal septum Present Regionally restricted 3B
TS21: maxilla Present Regionally restricted 3B
TS21: palatal shelf mesenchyme Present Regionally restricted 3B Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS21: tongue Present Regionally restricted 3B

Specimen 3E: embryonic day 13.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Regionally restricted 3E Slightly elevated lateral expression in palatal shelves at E13.5.
TS21: tongue Present Regionally restricted 3E

Specimen 4B: embryonic day 14.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS22: nasal septum Present Regionally restricted 4B
TS22: palatal shelf mesenchyme Present Regionally restricted 4B Expression in palatal shelf mesenchyme along the entire anteroposterior axis at each stage of palatal development.
TS22: tongue Present Regionally restricted 4B

Specimen 4E: embryonic day 14.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Present Regionally restricted 4E Expression restricted to oral-side mesenchyme of secondary palate at E14.5.
TS22: tongue Present Regionally restricted 4E

Specimen 5D: embryonic day 14.5 (more )
Note: Anterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5D Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5D Reduced expression in epithelial cell. Expression not detected at significant levels in the midline epithelia seam.

Specimen 5I: embryonic day 14.5 (more )
Note: Middle section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5I Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5I Reduced expression in epithelial cell. Expression not detected at significant levels in the midline epithelia seam.

Specimen 5N: embryonic day 14.5 (more )
Note: Posterior section.
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Strong 5N Elevated levels of expression in mesenchyme of the fusing palatal shelves at E14.5
TS22: palatal shelf epithelium Weak Regionally restricted 5N Reduced expression in epithelial cell. Expression not detected at significant levels in the midline epithelia seam.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory