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Gene Expression Data
Assay Details
Assay
Reference: J:124120 Rebustini IT, et al., Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling. Dev Biol. 2007 Aug 1;308(1):15-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6162503
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: anti-ZO-1
Results
Specimen 1G WT ZO-1: embryonic day 17.0 (more )
Note: Triple labeled: green - ZO-1 (Tjp1); red - phalloidin staining for actin; blue - nuclear staining.
Structure Level Pattern Image Note
TS25: submandibular gland Present Regionally restricted 1G WT merge , 1G WT ZO-1 Authors state that expression highlights lumen formation.
Specimen 1G -/- ZO-1: embryonic day 17.0 (more )
Note: Triple labeled: green - ZO-1 (Tjp1); red - phalloidin staining for actin; blue - nuclear staining.
Structure Level Pattern Image Note
TS25: submandibular gland Present Regionally restricted 1G Lama5-/- ZO-1 , 1G Lama5-/- merge Authors report that terminal buds lack lumens.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory