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Gene Expression Data
Assay Details
Assay
Reference: J:237110 Lee YG, et al., Coordinated lymphangiogenesis is critical in lymph node development and maturation. Dev Dyn. 2016 Dec;245(12):1189-1197
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197042
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: Anti-Prox1
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2A: embryonic day 12.5 (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS20: skin Present Regionally restricted 2C , 2B , 2A Expression was detected in migrating lymphatic endothelial cells from where forelimbs are attached to the body and along the lateral side.
Specimen 2D: embryonic day 12.5; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS20: skin Present Regionally restricted 2F , 2E , 2D Expression was detected in migrating lymphatic endothelial cells, which were confined to the boundary of the forelimb.
Specimen 2G E12.5 +/+: embryonic day 12.5 (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS20: hemolymphoid system Present Regionally restricted 2G E12.5 Vegfc+/+ Expression was detected in lymphatic endothelial cells in developing inguinal lymph node sites.
Specimen 2G E12.5 +/LacZ: embryonic day 12.5; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS20: hemolymphoid system Present Regionally restricted 2G E12.5 Vegfc+/LacZ Expression was detected in lymphatic endothelial cells in developing inguinal lymph node sites. Authors noted reduced migration to the anlagen sites in mutants.
Specimen 2G E14.5 +/+: embryonic day 14.5 (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2G E14.5 Vegfc+/+ Expression was detected in lymphatic endothelial cells in developing inguinal lymph node sites.
Specimen 2G E14.5 +/LacZ: embryonic day 14.5; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:6196899).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2G E14.5 Vegfc+/LacZ Expression was detected in lymphatic endothelial cells in developing inguinal lymph node sites. Authors noted reduced migration to the anlagen sites in mutants.
Specimen 2H +/+: embryonic day 14.5 (more )
Note: Double labeled: green - Prox1; red - Mki67 (assay MGI:6197047).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2H Vegfc+/+ Expression overlapped with Mki67 in proliferative lymphatic endothelial cells.
Specimen 2H +/LacZ: embryonic day 14.5; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: green - Prox1; red - Mki67 (assay MGI:6197047).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2H Vegfc+/LacZ Expression overlapped with Mki67 in proliferative lymphatic endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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