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Gene Expression Data
Assay Details
Assay
Reference: J:237110 Lee YG, et al., Coordinated lymphangiogenesis is critical in lymph node development and maturation. Dev Dyn. 2016 Dec;245(12):1189-1197
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197052
Gene symbol: Cd4
Gene name: CD4 antigen
Antibody: Anti-Cd4
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2I +/+: embryonic day 14.5 (more )
Note: Double labeled: red - Cd4; white - Pecam1 (assay MGI:6197053).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2I Vegfc+/+ Expression was detected in the LTi - a cluster of hematopoietic lymphoid inducer cells.

Specimen 2I +/LacZ: embryonic day 14.5; Vegfctm1Ali/Vegfc+ (more )
Note: Double labeled: red - Cd4; white - Pecam1 (assay MGI:6197053).
Structure Level Pattern Image Note
TS22: hemolymphoid system Present Regionally restricted 2I Vegfc+/LacZ Expression was detected in the LTi - a cluster of hematopoietic lymphoid inducer cells, which was smaller in the mutant.

Specimen 3B P1: postnatal day 1 (more )
Note: Triple labeled: red - Cd4; green - Lyve1 (assay MGI:6197056); blue - Pecam1 (assay MGI:6197053).
Structure Level Pattern Image Note
TS27: lymph node Present Regionally restricted 3B P1 Expression was detected in the T-cells population, which was separate from the Lyve1+ population of macrophages and lymphatic vessels.

Specimen 3B P2: postnatal day 2 (more )
Note: Triple labeled: red - Cd4; green - Lyve1 (assay MGI:6197056); blue - Pecam1 (assay MGI:6197053).
Structure Level Pattern Image Note
TS27: lymph node Present Regionally restricted 3B P2 Expression was detected in the T-cells population, which was separate from the Lyve1+ population of macrophages and lymphatic vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory