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Gene Expression Data
Assay Details
Assay
Reference: J:167064 L'honore A, et al., Pitx2 defines alternate pathways acting through MyoD during limb and somitic myogenesis. Development. 2010 Nov;137(22):3847-56
Assay type: RNA in situ
MGI Accession ID: MGI:6260207
Gene symbol: Myog
Gene name: myogenin
Probe: myogenin probe17
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2I: embryonic day 11.25; Pitx2tm2Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 2I
TS19: myotome Present 2I
Specimen 2J: embryonic day 11.25; Pitx2tm2Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Weak 2J Authors report decreased expression.
TS19: myotome Present 2J Authors state myotome expression is not delayed in Pitx2-/- embryos.
Specimen S1E: embryonic day 13.0; Pitx2tm2Sac/Pitx2+ (more )
Structure Level Pattern Image Note
TS21: forelimb Present S1E
Specimen S1F: embryonic day 13.0; Pitx2tm2Sac/Pitx2tm2Sac (more )
Structure Level Pattern Image Note
TS21: forelimb Present S1F Authors report expression patterns at E13.0 suggesting full recovery of expression.
Specimen S4A: embryonic day 13.0; Pitx2tm2Sac/Pitx2+, Pitx3tm1.1Jdr/Pitx3+ (more )
Structure Level Pattern Image Note
TS21: forelimb Present S4A
Specimen S4B: embryonic day 13.0; Pitx2tm2Sac/Pitx2+, Pitx3tm1.1Jdr/Pitx3tm1.1Jdr (more )
Structure Level Pattern Image Note
TS21: forelimb Present S4B
Specimen S4C: embryonic day 13.0; Pitx2tm2Sac/Pitx2tm2Sac, Pitx3tm1.1Jdr/Pitx3tm1.1Jdr (more )
Structure Level Pattern Image Note
TS21: forelimb Present S4C Authors report similar expression patterns as in Pitx2-/- embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory