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Gene Expression Data
Assay Details
Assay
Reference: J:243416 Ahn Y, et al., Multiple modes of Lrp4 function in modulation of Wnt/beta-catenin signaling during tooth development. Development. 2017 Aug 01;144(15):2824-2836
Assay type: RNA in situ
MGI Accession ID: MGI:6270006
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1F Control: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw molar Present 1F Control

Specimen 1F Lrp4mte/mte: embryonic day 15.5; Lrp4mte/Lrp4mte (more )
Structure Level Pattern Image Note
TS23: lower jaw molar Present 1F mte/mte
TS23: lower jaw Present Regionally restricted 1F mte/mte Expression is in a developing tooth and in a another domain distal to the molar.

Specimen S1 Control: embryonic day 14.5 (more )
Note: The authors state that control mice were either wild-type or heterozygous for either Lrp4mitt or Lrp4mte allele, all have been annotated.
Structure Level Pattern Image Note
TS22: lower jaw tooth Present S1_Control Shh

Specimen S1 Lrp4-/-: embryonic day 14.5; Lrp4mte/Lrp4mte (more )
Note: The authors state that the Lrp4-/- mutant was either homozygous Lrp4mitt or Lrp4mte, both have been annotated.
Structure Level Pattern Image Note
TS22: lower jaw tooth Weak S1_Lrp4-/- Shh

Specimen Lrp4-/-: embryonic day 14.5; Lrp4mitt/Lrp4mitt (more )
Structure Level Pattern Image Note
TS22: lower jaw tooth Weak

Specimen Control Lrp4mitt: embryonic day 14.5; Lrp4mitt/Lrp4+ (more )
Structure Level Pattern Image Note
TS22: lower jaw tooth Present

Specimen Control Lrp4mte: embryonic day 14.5; Lrp4mte/Lrp4+ (more )
Structure Level Pattern Image Note
TS22: lower jaw tooth Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory