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Gene Expression Data
Assay Details
Assay
Reference: J:243416 Ahn Y, et al., Multiple modes of Lrp4 function in modulation of Wnt/beta-catenin signaling during tooth development. Development. 2017 Aug 01;144(15):2824-2836
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6270133
Gene symbol: Lrp4
Gene name: low density lipoprotein receptor-related protein 4
Reporter: lacZ
Direct Detection
Results
Specimen 1C E12.5: embryonic day 12.5; Lrp4em1Krum/Lrp4+ (more )
Note: Fixative was 0.1% paraformaldehyde/0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS20: mandibular process Present Regionally restricted 1C E12.5 Expression is in the the two vestigial diastema tooth buds.
Specimen 1C E13.5: embryonic day 13.5; Lrp4em1Krum/Lrp4+ (more )
Note: Fixative was 0.1% paraformaldehyde/0.2% glutaraldehyde.
Structure Level Pattern Image Note
TS21: lower jaw Present Regionally restricted 1C E13.5 Expression is in the the two vestigial diastema tooth buds.
Specimen 1C E14.5: embryonic day 14.5; Lrp4em1Krum/Lrp4+ (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Strong Regionally restricted 1C E14.5 Expression is in the more proximal region of the dental epithelium where the first molar develops.
TS22: lower jaw Present Regionally restricted 1C E14.5 Expression is in the degenerating diastema.
Specimen 1E Lrp4+/LacZ: embryonic day 14.5; Lrp4em1Krum/Lrp4+ (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Strong Regionally restricted 1E +/LacZ Expression is in the more proximal region of the dental epithelium where the first molar develops.
TS22: lower jaw Weak Regionally restricted 1E +/LacZ Expression is in the degenerating diastema.
Specimen 1E Lpr4mitt/LacZ: embryonic day 14.5; Lrp4em1Krum/Lrp4mitt (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Present Regionally restricted 1E mitt/LacZ Expression is in the more proximal region of the dental epithelium where the first molar develops.
TS22: lower jaw Present Regionally restricted 1E mitt/LacZ Expression is in the diastema.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory