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Gene Expression Data
Assay Details
Assay
Reference: J:115860 Tada T, et al., Morphological study of the transition of haematopoietic sites in the developing mouse during the peri-natal period. Anat Histol Embryol. 2006 Aug;35(4):235-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6304429
Gene symbol: Vcam1
Gene name: vascular cell adhesion molecule 1
Antibody: Anti-VCAM1
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 2a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver parenchyma Present Widespread 2a Expressed in stromal reticular cells.
TS20: liver vasculature Present 2a Coexpressed with Fn1 in endothelial cells.

Specimen 2b: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: liver parenchyma Present 2b Decreased expression. Few areas of Vcam1 and Fn1 co-expressed were seen.
TS26: liver vasculature Present 2b Decreased expression. Few areas of Vcam1 and Fn1 co-expressed were seen. Expressed in endothelial cells.

Specimen 4a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spleen Present 4a Expressed in stromal cells and endothelial cells.

Specimen 4b: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: spleen marginal zone Strong 4b
TS28: spleen red pulp Strong 4b
TS28: spleen white pulp Weak 4b Little expression.

Specimen 6a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: femur Present Regionally restricted 6a Expressed on the surface layer of trabecular bone near the epiphyseal plate, spreading throughout the hematopoietc compartment in the middle of the diaphysis.

Specimen 6b: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: femur Present Regionally restricted 6b Expression spred to the haematopoietic compartments. Co-expressed with Fn1 in sinus endothelial cells.

Specimen 6c: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: femur epiphysis Present Regionally restricted 6c Coexpression with Fn1 increased markedly on the surface layers of trabecular bone.

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: liver parenchyma Present Decreased abruptly.
TS24: liver vasculature Present Decreased abruptly.
TS24: spleen Present Expressed in stromal cells and endothelial cells.
TS24: femur Present Regionally restricted Expressed around the bone trabeculae near the end of the diaphysis.

Specimen not shown: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: liver parenchyma Ambiguous Gradually decreased expression.
TS28: liver vasculature Present Expressed in endothelial cells. No coexpression with Fn1.

Specimen not shown: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spleen Present Expressed in stromal cells and endothelial cells.

Specimen not shown: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: spleen marginal sinus Present
TS27: spleen red pulp Present

Specimen not shown: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: spleen periarteriolar lymphatic sheath Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory