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Gene Expression Data
Assay Details
Assay
Reference: J:188806 Hurd EA, et al., Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 2012 Sep;129(9-12):308-23
Assay type: RNA in situ
MGI Accession ID: MGI:6305146
Gene symbol: Gata3
Gene name: GATA binding protein 3
Probe: Gata3 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4P: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4P Expression was detected in the lateral compartment of the otocyst.
Specimen 4Q: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4Q Expression was detected in the lateral compartment of the otocyst.
Specimen 4R: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4R Ventromedial expression was present in the mutant otocysts, but the dorsolateral expression was absent.
Specimen 4S: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4S Expression was detected in the lateral compartment of the otocyst, as in wild type.
Specimen 4T: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4T Expression was preserved in the ventral domain of the conditional mutant otocyst, but the dorsal expression was reduced.
Specimen 4U: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4U Expression was detected in the ventral domain of the otocyst.
Specimen 4V: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4V Expression was detected in the ventral domain of the otocyst.
Specimen 4W: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4W Ventromedial expression was present in the mutant otocysts, but the dorsolateral expression was absent.
Specimen 4X: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4X Expression was detected in the ventral domain of the otocyst.
Specimen 4Y: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4Y Expression was preserved in the ventral domain of the conditional mutant otocyst, but the dorsal expression was reduced.
Specimen 10D: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10D Expression was detected in the lateral crista.
Specimen 10J: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10J Expression was detected in the lateral crista.
Specimen 10P: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10P Expression was detected in the lateral crista.
Specimen 10V: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: semicircular canal Absent 10V
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory