About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:188806 Hurd EA, et al., Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 2012 Sep;129(9-12):308-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6305194
Gene symbol: Jag1
Gene name: jagged 1
Antibody: anti-Jagged1(C-20): sc-6011
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 9A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present 9A
Specimen 9B: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present 9B
Specimen 9C: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: otocyst Present 9C Expression was detected in the otocyst, as in wild type.
Specimen 9D: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present 9D Expression was detected in the otocyst, as in wild type.
Specimen 9E: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present 9E Expression was detected in the otocyst, as in wild type.
Specimen 10B: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10B Expression was detected in the lateral cristae.
Specimen 10H: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10H Expression was detected in the lateral cristae.
Specimen 10N: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS19: semicircular canal Present Regionally restricted 10N Expression was detected in the lateral cristae.
Specimen 10T: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: semicircular canal Absent 10T No expression was detected in the dorsal compartment of the conditional mutant inner ears.
Specimen S2E: embryonic day 12.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS21: lateral semicircular canal Present Regionally restricted S2E Expression was detected in the lateral cristae.
Specimen S2F: embryonic day 12.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lateral semicircular canal Present Regionally restricted S2F Expression was detected in the lateral cristae.
Specimen S2G: embryonic day 12.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS21: lateral semicircular canal Present Regionally restricted S2G Expression was detected in the lateral cristae.
Specimen S2H: embryonic day 12.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lateral semicircular canal Absent S2H No expression was detected in the dorsal compartment of the conditional mutant inner ears.
Specimen Table 1 +/+ E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 Gt/+ E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 Gt/Gt E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 Cond. het: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 CKO E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 +/+ E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 Gt/+ E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 Cond. het: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 CKO E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory