Rhoa Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:226923 Bowen CJ, et al., Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation. Dev Biol. 2015 Nov 1;407(1):145-57
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6306459
Gene symbol:	Rhoa
Gene name:	ras homolog family member A

Antibody:	anti-active RhoA-GTP
Detection system:	Alexa Fluor 568

Results

5C ©

Specimen 5C: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: aortic valve leaflet	Present		5C	Authors report expression in wild type valves.

5G ©

Specimen 5G: embryonic day 18.5; Cdh11^tm1Mta/Cdh11^tm1Mta (more

)

Structure	Level	Pattern	Image	Note
TS26: aortic valve leaflet	Trace		5G	Authors report expression reduced 3.0 fold.

8E +/+ ©

Specimen 8E +/+: postnatal month 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: aortic valve	Very strong		8E +/+	Expression elevated compared to fetal stage.

8E -/- ©

Specimen 8E -/-: postnatal month 10; Cdh11^tm1Mta/Cdh11^tm1Mta (more

)

Structure	Level	Pattern	Image	Note
TS28: aortic valve	Trace		8E -/-	Expression remained significantly decreased in mutant valve leaflets.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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