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Gene Expression Data
Assay Details
Assay
Reference: J:181271 Westmoreland JJ, et al., Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation. Dev Dyn. 2012 Mar;241(3):583-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6343210
Gene symbol: Cldn2
Gene name: claudin 2
Antibody: Claudin-2 antibody (E3920)
Detection system: Secondary antibody coupled to Cy3
Assay notes: Two antibodies were described, but the one used in this assay was not specified. Either MGI:6324575 or MGI:6324582 could have been used.
Results
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Absent
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pancreas Absent
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas epithelium Absent
TS23: metanephros epithelium Present
Specimen 3B: embryonic day 18.5 (more )
Note: Double labeled: red - Cldn2; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS26: pancreatic duct Present Regionally restricted 3B Co-expression with Tjp1 was noted in tight junctions of pancreatic ductal epithelial cells.
Specimen 3C: postnatal day 5 (more )
Note: Double labeled: red - Cldn2; green - Cdh1 (assay MGI:6343239).
Structure Level Pattern Image Note
TS28: pancreatic duct Present Regionally restricted 3C Expression was detected in the lumen of the ductal pancreatic epithelium, which was demarcated by Cdh1 staining.
Specimen 3D: postnatal day 5 (more )
Note: Double labeled: red - Cldn2; green - Tjp1 (assay MGI:6343238).
Structure Level Pattern Image Note
TS28: pancreatic duct Present Regionally restricted 3D Expression was detected in the lumen of the ductal pancreatic epithelium. Co-expression with Tjp1 was noted in tight junctions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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