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Gene Expression Data
Assay Details
Assay
Reference: J:170258 Mavromatakis YE, et al., Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6343552
Gene symbol: Foxa2
Gene name: forkhead box A2
Antibody: anti-HNF3b
Assay notes: Two antibodies were described, but the one used in this assay was not specified. Either MGI:1338477 or MGI:5562562 could have been used.
Results
Specimen 1B E8.5 Control: embryonic day 8.5; Foxa2tm1Khk/Foxa2tm1Khk (more )
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 1B E8.5 Control Expression was detected in ventral midbrain.
Specimen 1B E8.5 Foxa2-Wnt1 cko: embryonic day 8.5; Foxa2tm1Khk/Foxa2tm1Khk, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: future midbrain floor plate Present Regionally restricted 1B E8.5 Foxa2-Wnt1 cko Expression in the conditional mutant is deleted from the ventral midbrain except in the medial floor plate.
Specimen 1B E9.5 Control: embryonic day 9.5; Foxa2tm1Khk/Foxa2tm1Khk (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 1B E9.5 Control Expression was detected in ventral midbrain.
Specimen 1B E9.5 Foxa2-Wnt1 cko: embryonic day 9.5; Foxa2tm1Khk/Foxa2tm1Khk, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: future midbrain floor plate Present Regionally restricted 1B E9.5 Foxa2-Wnt1 cko Expression in the conditional mutant is deleted from the ventral midbrain except in the medial floor plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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