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Gene Expression Data
Assay Details
Assay
Reference: J:276705 Suckau O, et al., LPA1 , LPA2 , LPA4 , and LPA6 receptor expression during mouse brain development. Dev Dyn. 2019 May;248(5):375-395
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6363159
Gene symbol: Lpar1
Gene name: lysophosphatidic acid receptor 1
Antibody: anti-LPA1
Detection system: Alexa Fluor 488
Results
Specimen 4A Wt: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong Regionally restricted 4A Wt Strong expression in stem cells o subgranular zone of hippocampus.
Specimen 4A LPA1 KO: postnatal day 15; Lpar1tm1Jch/Lpar1tm1Jch (more )
Structure Level Pattern Image Note
TS28: brain Absent 4A LPA1 KO
Specimen 4B: postnatal day 15 (more )
Note: Double labeled: green - Lpar1; red - Tubb3 (assay MGI:6363161).
Structure Level Pattern Image Note
TS28: neocortex Trace Regionally restricted 4B LPA1 , 4B overlay Expression barely observable in neuroblasts in cortex.
Specimen 4C: postnatal day 15 (more )
Note: Double labeled: green - Lpar1; red - Gfap (assay MGI:6363162).
Structure Level Pattern Image Note
TS28: neocortex Present Regionally restricted 4C LPA1 , 4C overlay Expression in astrocytes in both cell somal and astocytes processes.
Specimen 4D Gyrus dentatus: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong Regionally restricted 4D Gyrus dentatus Strong expression in stem cells of subgranular zone of hippocampus.
Specimen 4D Cerebellum: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Strong Regionally restricted 4D Cerebellum Strong expression in white matter of arbor vitae of cerebellum.
TS28: cerebellum molecular layer Strong 4D Cerebellum
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
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