Gene Expression Data
Assay Details
Assay
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Reference:
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J:122556
Inoue T, et al., Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo. Dev Biol. 2007 Jun 15;306(2):669-84
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6377209
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Gene symbol:
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Zic2
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Gene name:
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zinc finger protein of the cerebellum 2
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Probe:
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Zic2 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
1A:
embryonic day 7.0
(more )
Specimen
1A:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 7.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS10: embryo |
Present |
Widespread |
1A
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Expressed broadly in both extraembryonic and embryonic components of egg cylinder.
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TS10: extraembryonic component |
Present |
Widespread |
1A
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Expressed broadly in both extraembryonic and embryonic components of egg cylinder.
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Specimen
1B:
embryonic day 7.5
(more )
Specimen
1B:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: embryo ectoderm |
Present |
Regionally restricted |
1B
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Increased expression, first in anterior ectoderm, then in mesenchyme of headfold.
|
TS11: head mesenchyme |
Present |
Regionally restricted |
1B
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Increased expression, first in anterior ectoderm, then in mesenchyme of headfold.
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Specimen
1C:
embryonic day 7.5
(more )
Specimen
1C:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: head mesenchyme |
Present |
Regionally restricted |
1C
|
Increased expression in mesoderm of headfold.
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Specimen
1D:
embryonic day 8.0
(more )
Specimen
1D:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS12: neural fold |
Present |
Regionally restricted |
1D
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Expression in dorsal neural folds.
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TS12: somite |
Present |
Regionally restricted |
1D
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Expression in somites, with enhancements in a few caudal somites
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TS12: unsegmented mesenchyme |
Present |
Regionally restricted |
1D
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Expression in anterior presomitic mesoderm, .
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Specimen
1E:
embryonic day 8.0
(more )
Specimen
1E:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS12: neural fold |
Present |
Regionally restricted |
1E
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Expression in dorsal neural folds.
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TS12: somite |
Present |
Regionally restricted |
1E
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Expression in somites, with enhancements in a few caudal somites
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TS12: unsegmented mesenchyme |
Present |
Regionally restricted |
1E
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Expression in anterior presomitic mesoderm, .
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Specimen
1F:
embryonic day 8.5
(more )
Specimen
1F:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: neural fold |
Present |
Regionally restricted |
1F
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Expression in dorsal neural folds.
|
TS13: somite |
Present |
Regionally restricted |
1F
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Expression in somites, with enhancements in a few caudal somites.
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TS13: unsegmented mesenchyme |
Present |
Regionally restricted |
1F
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Expression in anterior presomitic mesoderm.
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Specimen
1G:
embryonic day 8.5
(more )
Specimen
1G:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: neural fold |
Present |
Regionally restricted |
1G
|
Expression in dorsal neural folds.
|
TS13: somite |
Present |
Regionally restricted |
1G
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Expression in somites, with enhancements in a few caudal somites
|
TS13: unsegmented mesenchyme |
Present |
Regionally restricted |
1G
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Expression in anterior presomitic mesoderm, .
|
Specimen
1H:
embryonic day 8.5
(more )
Specimen
1H:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: neural fold |
Present |
Regionally restricted |
1H
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Expression in dorsal neural folds.
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TS14: somite |
Present |
Regionally restricted |
1H
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Expression in somites, with enhancements in a few caudal somites
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TS14: unsegmented mesenchyme |
Present |
Regionally restricted |
1H
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Expression in anterior presomitic mesoderm.
|
Specimen
1I:
embryonic day 9.0
(more )
Specimen
1I:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: neural fold |
Present |
Regionally restricted |
1I
|
Expression in dorsal neural folds.
|
TS14: somite |
Present |
Regionally restricted |
1I
|
Expression in somites, with enhancements in a few caudal somites
|
TS14: unsegmented mesenchyme |
Present |
Regionally restricted |
1I
|
Expression in anterior presomitic mesoderm.
|
Specimen
2A:
embryonic day 10.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
2A
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In 64% of embryos, expression in presomitic mesoderm and somite detected as 2 distinct stripes.
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TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2A
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In 64% of embryos, expression in presomitic mesoderm and somite detected as 2 distinct stripes.
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TS17: tail neural tube |
Present |
Regionally restricted |
2A
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Expression in caudal end of neural tube.
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Specimen
2B:
embryonic day 10.5
(more )
Specimen
2B:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
2B
|
In 64% of embryos, expression in presomitic mesoderm and somite detected as 2 distinct stripes. In 2 of 19 embryos examined, expression in S1 (most newly formed somite) was weaker than in S0 (forming somite).
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TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2B
|
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TS17: tail neural tube |
Present |
Regionally restricted |
2B
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Expression in caudal end of neural tube.
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Specimen
2C:
embryonic day 10.5
(more )
Specimen
2C:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
2C
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In 5 of 19 embryo examined, expression as a single broad stripe in which anterior half of stripe corresponded to S0 (forming somite) and posterior half of stripe to S-1 (prospective somite).
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TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2C
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In 5 of 19 embryo examined, expression as a single broad stripe in which anterior half of stripe corresponded to S0 (forming somite) and posterior half of stripe to S-1 (prospective somite).
|
TS17: tail neural tube |
Present |
Regionally restricted |
2C
|
Expression in caudal end of neural tube.
|
Specimen
2I:
embryonic day 10.5
(more )
Specimen
2I:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
2I
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Two stripes of expression corresponding to S0 (forming somite) and S1 (most newly formed somite). Weaker expression in segmented somites with slight enhancement in anterior compartments.
|
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2I
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Weak expression in anterior part of S-1 (prospective somite).
|
TS17: tail neural tube |
Present |
Regionally restricted |
2I
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Expression in caudal end of neural tube.
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Specimen
2J:
embryonic day 10.5
(more )
Specimen
2J:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
2J
|
Single broad stripe in which anterior half of stripe corresponded to S0 (forming somite). Weaker expression in segmented somites with slight enhancement in anterior compartments.
|
TS17: tail unsegmented mesenchyme |
Present |
Regionally restricted |
2J
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Single broad stripe in which posterior half of stripe corresponded to S-1 (prospective somite).
|
TS17: tail neural tube |
Present |
Regionally restricted |
2J
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Expression in caudal end of neural tube.
|
Specimen
2K:
embryonic day 10.5
(more )
Specimen
2K:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S1A:
embryonic day 10.5
(more )
Specimen
S1A:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6J
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: tail somite |
Present |
Regionally restricted |
S1A
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Expression pattern mostly consistent with that of Zic protein localization. Expression in S0 (forming somite) and S1 (most newly formed somite).
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