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Gene Expression Data
Assay Details
Assay
Reference: J:281617 Balounova J, et al., Toll-like receptor 2 expression on c-kit(+) cells tracks the emergence of embryonic definitive hematopoietic progenitors. Nat Commun. 2019 Nov 15;10(1):5176
Assay type: Recombinase reporter
MGI Accession ID: MGI:6385339
Gene symbol: Tlr2
Gene name: toll-like receptor 2
Reporter: YFP
Direct Detection
Results
Specimen Fig. 2 E8.5: embryonic day 8.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tlr2tm1(cre)Dfil/Tlr2+ (more )
Note: Conditional mutant. For E8.5-E10.5 whole embryos were imaged with a Nikon AZ-100 confocal microscope equipped with a 4 objective.
Structure Level Pattern Image Note
TS13: hematopoietic system Present 2left column top E8.5 , 2right column top E8.5 Activity first appeared at E8.5.
Specimen Fig. 2 E9.5: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tlr2tm1(cre)Dfil/Tlr2+ (more )
Note: Conditional mutant. For E8.5-E10.5 whole embryos were imaged with a Nikon AZ-100 confocal microscope equipped with a 4 objective.
Structure Level Pattern Image Note
TS15: hematopoietic system Present 2left column middle E9.5 , 2right column middle E9.5 present in hematopoietic progenitors
Specimen Fig. 2 E10.5: embryonic day 10.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tlr2tm1(cre)Dfil/Tlr2+ (more )
Note: Conditional mutant. For E8.5-E10.5 whole embryos were imaged with a Nikon AZ-100 confocal microscope equipped with a 4 objective.
Structure Level Pattern Image Note
TS17: hematopoietic system Present 2left column bottom E10.5 , 2right column bottom E10.5
Specimen Sup Fig. 4D: embryonic day 11.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tlr2tm1(cre)Dfil/Tlr2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: head Present S4D E11.5 HEAD reactivity in macrophases in head
TS19: liver Present S4D E11.5 FL reactivity in macrophases in fetal liver
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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