Dkk2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:136041 Gage PJ, et al., The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol. 2008 May 1;317(1):310-24
Assay type:	RNA in situ
MGI Accession ID:	MGI:6385651
Gene symbol:	Dkk2
Gene name:	dickkopf WNT signaling pathway inhibitor 2

Probe:	Dkk2 probe3
Probe preparation:	labelled with digoxigenin

Results

1B ii ©

Specimen 1B ii: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: perioptic mesenchyme	Present	Regionally restricted	1B ii	Expression in periocular mesenchyme surrounding optic cup.
TS20: extrinsic ocular pre-muscle mass	Absent		1B ii	No expression in eye muscle.

1B iii ©

Specimen 1B iii: embryonic day 12.5; Pitx2^tm2Sac/Pitx2^tm2Sac (more

)

Structure	Level	Pattern	Image	Note
TS20: eye	Absent		1B iii

1B iv ©

Specimen 1B iv: embryonic day 12.5; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺, Pitx2^tm1.1Sac/Pitx2^tm2Sac (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: eye	Absent		1B iv

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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