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Gene Expression Data
Assay Details
Assay
Reference: J:136705 Jonckheere N, et al., Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. Dev Biol. 2008 Jun 15;318(2):224-35
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386392
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-Pdx1
Detection system: Cy3
Results
Specimen 2I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas epithelium Present Regionally restricted 2I Expression in dorsal and ventral pancreatic epithelium.
Specimen 2J: embryonic day 13.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS21: pancreas epithelium Present Regionally restricted 2J Authors report that pancreatic epithelium showed less branching and significant reduction in size compared to controls.
Specimen 2L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pancreas epithelium Present 2L Expression in dorsal and ventral pancreatic epithelium.
Specimen 2M: embryonic day 12.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Structure Level Pattern Image Note
TS20: pancreas epithelium Present 2M No difference between mutant and control embryos at E12.5.
Specimen 8C/E: embryonic day 12.5 (more )
Note: Double labeled: red - Pdx1; green - Pygo2 (assay MGI:6386390).
Structure Level Pattern Image Note
TS21: pancreas epithelium Present 8E , 8C
Specimen 8F/H: embryonic day 12.5; Pygo2tm1.1Xdai/Pygo2tm1.2Xdai, Tg(Pdx1-cre)6Cvw/0 (more )
Note: Conditional mutant. Double labeled: red - Pdx1; green - Pygo2 (assay MGI:6386390).
Structure Level Pattern Image Note
TS21: pancreas epithelium Present 8H , 8F
Specimen 9D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pancreas epithelium Present Regionally restricted 9D Authors report that the branching pattern of dorsal and ventral pancreatic epithelium indistinguishable between mutant and control littermates.
Specimen 9E: embryonic day 13.5; Pygo2tm1.1Xdai/Pygo2tm1.2Xdai, Tg(Pdx1-cre)6Cvw/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: pancreas epithelium Present Regionally restricted 9E Authors report that the branching pattern of dorsal and ventral pancreatic epithelium indistinguishable between mutant and control littermates.
Specimen S3A: embryonic day 10.5 (more )
Note: Double labeled: red - Pdx1; green - Isl1 (assay MGI:6386412).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted S3A
Specimen S3B: embryonic day 10.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Note: Double labeled: red - Pdx1; green - Isl1 (assay MGI:6386412).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted S3B
Specimen S3C: embryonic day 10.5 (more )
Note: Double labeled: red - Pdx1; green - Pbx1 (assay MGI:6386413).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted S3C
Specimen S3D: embryonic day 10.5; Pygo2tm1.2Xdai/Pygo2tm1.2Xdai (more )
Note: Double labeled: red - Pdx1; green - Pbx1 (assay MGI:6386413).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted S3D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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