Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:136719
Maretto S, et al., Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol. 2008 Jun 1;318(1):184-93
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:6387012
|
Gene symbol:
|
Afp
|
Gene name:
|
alpha fetoprotein
|
Probe:
|
AFP probe4
|
Probe preparation:
|
Antisense RNA
|
|
Results
|
Specimen
4K:
embryonic day 8.5
(more )
Specimen
4K:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: yolk sac |
Present |
|
4K
|
Expression is along the lateral edges of the visceral yolk sac.
|
TS13: foregut diverticulum |
Present |
Regionally restricted |
4K
|
Expression outlines the anterior intestinal portal.
|
Specimen
4L:
(close )
Genetic Background:
|
involves: 129S/SvEv * C57BL/6J
|
Mutant Allele(s):
|
Flrt3tm1Rob/Flrt3tm1Rob
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: yolk sac |
Present |
Regionally restricted |
4L
|
Expression along the lateral adges is the same as in wild-type but the mutant lacks a contiguous domain of expression across the anterior ventral midline.
|
|