Gene Expression Data
Assay Details
Assay
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Reference:
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J:281795
Raju S, et al., Kinase domain dimerization drives RIPK3-dependent necroptosis. Sci Signal. 2018 Aug 21;11(544)
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6404415
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Gene symbol:
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Ripk3
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Gene name:
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receptor-interacting serine-threonine kinase 3
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Results
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Specimen
1C Liver Ripk3+/D161N Ripk1+/+:
embryonic day 11.5; Ripk3tm2Vmd/Ripk3 +
(more )
Specimen
1C Liver Ripk3<+/D161N> Ripk1<+/+>:
(close )
Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Ripk3tm2Vmd/Ripk3+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: liver |
Absent |
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1C Liver Ripk3+/D161N Ripk1+/+
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Specimen
1C Liver Ripk3<+/D161N> Ripk1<-/->:
(close )
Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Ripk1tm1.1Vmd/Ripk1tm1.1Vmd Ripk3tm2Vmd/Ripk3+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: liver |
Present |
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1C Liver Ripk3+/D161N Ripk1-/-
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The Ripk3<+/D161N> Ripk1<-/-> embryos showed abnormal autophosphorylation in the liver.
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Specimen
1C Placenta Ripk3+/D161N Ripk1+/+:
embryonic day 11.5; Ripk3tm2Vmd/Ripk3 +
(more )
Specimen
1C Placenta Ripk3<+/D161N> Ripk1<+/+>:
(close )
Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Ripk3tm2Vmd/Ripk3+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: placenta |
Absent |
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1C Placenta Ripk3+/D161N Ripk1+/+
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Specimen
1C Placenta Ripk3<+/D161N> Ripk1<-/->:
(close )
Genetic Background:
|
involves: C57BL/6N
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Mutant Allele(s):
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Ripk1tm1.1Vmd/Ripk1tm1.1Vmd Ripk3tm2Vmd/Ripk3+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: placenta |
Present |
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1C Placenta Ripk3+/D161N Ripk1-/-
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The Ripk3<+/D161N> Ripk1<-/-> embryos showed abnormal autophosphorylation in the placenta.
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