Gene Expression Data
Assay Details
Assay
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Reference:
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J:242313
Forge A, et al., Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear. PLoS Genet. 2017 Mar;13(3):e1006692
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6414888
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Gene symbol:
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Prkcz
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Gene name:
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protein kinase C, zeta
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Results
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Specimen
11E normal:
postnatal day 1
(more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Specimen
11E normal:
(close )
Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
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Structure |
Level |
Pattern |
Image |
Note |
TS27: organ of Corti |
Present |
Regionally restricted |
11E'
,
11E
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Expression localised to the apical surface of the outer and inner hair cells, specifically on the medial side.
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Specimen
11F affected:
(close )
Genetic Background:
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involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
|
Double labeled: green - aPKC; red - actin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: organ of Corti |
Present |
Regionally restricted |
11F'
,
11F
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Expression is seen at the surface of hair cells, but the distribution is symmetric around the entire circumference and across their apical surface, not asymmetric as is seen in normal animals.
|
Specimen
12E normal:
postnatal day 1
(more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Specimen
12E normal:
(close )
Genetic Background:
|
involves: C57BL/6
|
Age:
|
postnatal day 1
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Paraformaldehyde
|
Note:
|
Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: macula of utricle |
Present |
Regionally restricted |
12E'
,
12E
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Expression is detected at the surface of hair cells, most strongly on the medial side.
|
Specimen
12F affected:
(close )
Genetic Background:
|
involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
|
postnatal day 1
|
Sex:
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Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Paraformaldehyde
|
Note:
|
Double labeled: green - aPKC; red - actin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: macula of utricle |
Present |
Regionally restricted |
12F
,
12F'
|
Expression is seen at the surface of hair cells, but the distribution is symmetric around the entire circumference and across their apical surface, not asymmetric as is seen in normal animals.
|
Specimen
13E normal:
postnatal day 1
(more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Specimen
13E normal:
(close )
Genetic Background:
|
involves: C57BL/6
|
Age:
|
postnatal day 1
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Paraformaldehyde
|
Note:
|
Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: crista ampullaris |
Present |
Regionally restricted |
13E'
,
13E
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Expression is seen at the surface of hair cells, most strongly on the medial side.
|
Specimen
13F affected:
(close )
Genetic Background:
|
involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
|
postnatal day 1
|
Sex:
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Not Specified
|
Type:
|
whole mount
|
Fixation:
|
Paraformaldehyde
|
Note:
|
Double labeled: green - aPKC; red - actin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: crista ampullaris |
Present |
Regionally restricted |
13F
,
13F'
|
Expression is seen at the surface of hair cells, but the distribution is symmetric, not asymmetric as is seen in normal animals.
|
|