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Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416157
Gene symbol: Eomes
Gene name: eomesodermin
Results
Specimen 1A: embryonic day 12.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Eomes; red - Nf2 (assay MGI:6416155).
Structure Level Pattern Image Note
TS20: telencephalon Present 1A right
Specimen 1B: embryonic day 12.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Eomes; red - Nf2 (assay MGI:6416155).
Structure Level Pattern Image Note
TS20: telencephalon Present 1B right
Specimen 4I: embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Eomes; green - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: hippocampus Present Regionally restricted 4I Expression was detected in intermediate progenitors of pyramidal neurons in the subventricular zone.
TS22: telencephalon Present Regionally restricted 4I Expression was detected in progenitors of the dentate granule neurons. Immunopositive cells migrated as a stream from the subventricular zone towards the pia and into the dentate anlage.
Specimen 4J: embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Eomes; green - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: hippocampus Present Regionally restricted 4J Normal expression was detected in intermediate progenitors of pyramidal neurons in the subventricular zone of the conditional mutant.
TS22: telencephalon Present Regionally restricted 4J Normal expression was detected in progenitors of the dentate granule neurons of the conditional mutant.
Specimen 4K: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Triple labeled: green - Eomes; blue - Bcl11b (assay MGI:6416329); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: hippocampus Present 4K
Specimen 4L: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Triple labeled: green - Eomes; blue - Bcl11b (assay MGI:6416329); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: hippocampus Present 4L
Specimen S6A: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Triple labeled: green - Eomes; blue - Bcl11b (assay MGI:6416329); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted S6A Expression was detected in intermediate progenitors in the neocortex.
Specimen S6B: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Triple labeled: green - Eomes; blue - Bcl11b (assay MGI:6416329); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted S6B The number of Eomes-immunopositive intermediate progenitors was not affected by the conditional mutation.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory