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Gene Expression Data
Assay Details
Assay
Reference: J:257927 Fairchild CL, et al., RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430607
Gene symbol: Lhx2
Gene name: LIM homeobox protein 2
Results
Specimen 7A: postnatal day 20 (more )
Note: Double labeled: red - Lhx2; green - Glul (assay MGI:6430610). The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 7A , 7A'' Expression was detected in Muller glial cells.
Specimen 7B: postnatal day 20; Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Lhx2; green - Glul (assay MGI:6430610).
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted 7B , 7B'' Immunolabeled ectopic Muller glia cells were found in the outer plexiform layer and the outer nuclear layer.
TS28: retina outer plexiform layer Present Regionally restricted 7B , 7B'' Immunolabeled ectopic Muller glia cells were found in the outer plexiform layer and the outer nuclear layer.
Specimen 8E: postnatal day 20 (more )
Note: Double labeled: green - Lhx2; red - Gfap (assay MGI:6430612).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 8E , 8E' Expression was detected in Muller glial cells.
Specimen 8F: postnatal day 20; Socs7tm1b(EUCOMM)Wtsi/Socs7tm1b(EUCOMM)Wtsi (more )
Note: Double labeled: green - Lhx2; red - Gfap (assay MGI:6430612).
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8F' , 8F Some Muller glial cells were displaced towards the outer nuclear layer in the knockout retinas.
Specimen S4A: postnatal day 20 (more )
Note: Double labeled: green - Lhx2; red - Arr3 (assay MGI:6430500). The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S4A , S4A' Muller glial cells were immunolabeled with Lhx2.
Specimen S4B: postnatal day 20; Dab1tm1Cpr/Dab1+, Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Lhx2; red - Arr3 (assay MGI:6430500).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted S4B , S4B' Some displaced/ectopic Muller glial cells were noted in the mutant retina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory