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Gene Expression Data
Assay Details
Assay
Reference: J:245773 Paikari A, et al., The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport. Development. 2017 Oct 15;144(20):3731-3743
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6434319
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: Anti-CD31 (ab28364)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S2D: embryonic day 18.5; Mirc5tm1.1Blel/Mirc5+ (more )
Note: Double labeled: green - Pecam1; red - Mirc5 (assay MGI:6434223).
Structure Level Pattern Image Note
TS26: extraembryonic blood vessel Present Regionally restricted S2D higher mag center , S2D top , S2D higher mag left Expression was detected in the allantois-derived endothelial cells, but did not colocalize in the mCherry-labeled trophoblastic cells of the labyrinth.
Specimen 5A WT: embryonic day 12.5 (more )
Note: Double labeled: green - Pecam1; red - Krt8 (assay MGI:6434480).
Structure Level Pattern Image Note
TS20: extraembryonic blood vessel Present Regionally restricted 5A WT Expression was detected in endothelial cells surrounding fetal vasculature of the labyrinth.
Specimen 5A KO: embryonic day 12.5; Mirc5tm1Jae/Mirc5tm1Jae (more )
Note: Double labeled: green - Pecam1; red - Krt8 (assay MGI:6434480).
Structure Level Pattern Image Note
TS20: extraembryonic blood vessel Present Regionally restricted 5A KO Measurements of the fetal vasculature surface areas were significantly reduced in labyrinths of the knockout placenta.
Specimen 5B WT: embryonic day 15.5 (more )
Note: Double labeled: green - Pecam1; red - Krt8 (assay MGI:6434480).
Structure Level Pattern Image Note
TS23: extraembryonic blood vessel Present Regionally restricted 5B WT Expression was detected in endothelial cells surrounding fetal vasculature of the labyrinth.
Specimen 5B KO: embryonic day 15.5; Mirc5tm1Jae/Mirc5tm1Jae (more )
Note: Double labeled: green - Pecam1; red - Krt8 (assay MGI:6434480).
Structure Level Pattern Image Note
TS23: extraembryonic blood vessel Present Regionally restricted 5B KO Measurements of the fetal vasculature surface areas were significantly reduced in labyrinths of the knockout placenta.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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