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Gene Expression Data
Assay Details
Assay
Reference: J:139183 Smagulova FO, et al., GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development. BMC Dev Biol. 2008;8:67
Assay type: RNA in situ
MGI Accession ID: MGI:6434386
Gene symbol: Lhx9
Gene name: LIM homeobox protein 9
Probe: Lhx9a/b probe
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Probe detects both isoforms Lhx9alpha and Lhx9beta (see Fig. 1B).
Results
Specimen 3C wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: atrioventricular sulcus Weak 3C left
TS19: heart ventricle Weak 3C left
TS19: outflow tract Weak 3C left

Specimen 3C -/-: embryonic day 11.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS19: atrioventricular sulcus Present 3C right Strongly enhanced expression compared with the wild-type.
TS19: heart ventricle Present 3C right Strongly enhanced expression compared with the wild-type.
TS19: outflow tract Present 3C right Strongly enhanced expression compared with the wild-type.

Specimen 3D wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: atrioventricular sulcus Weak 3D left
TS19: heart ventricle Weak 3D left
TS19: outflow tract Weak 3D left

Specimen 3D -/-: embryonic day 11.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS19: atrioventricular sulcus Present 3D right Strongly enhanced expression compared with the wild-type.
TS19: heart ventricle Present 3D right Strongly enhanced expression compared with the wild-type.
TS19: outflow tract Present 3D right Strongly enhanced expression compared with the wild-type.

Specimen 3E wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Trace 3E left Almost extinguished expression.

Specimen 3E -/-: embryonic day 12.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS20: heart Strong 3E right

Specimen 3F wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Trace 3F left Almost extinguished expression.

Specimen 3F -/-: embryonic day 12.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS20: heart Strong 3F right

Specimen 3G wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart Trace 3G left Almost extinguished expression.

Specimen 3G -/-: embryonic day 13.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS21: heart Strong 3G right

Specimen 3H wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: heart Trace 3H left Almost extinguished expression.

Specimen 3H -/-: embryonic day 13.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS21: heart Strong 3H right

Specimen 5A wt: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: septum transversum Strong 5A wt inset , 5A top left
TS15: hindlimb ridge Present 5A top left

Specimen 5A -/-: embryonic day 9.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS15: septum transversum Strong 5A -/- inset , 5A top right Slightly lower expression compared with the wild-type.
TS15: hindlimb ridge Present 5A top right

Specimen 5B wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Trace 5B left Almost extinguished expression.

Specimen S2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: testis Present S2A

Specimen S2B: embryonic day 13.5; Zfpm2tm1Sho/Zfpm2tm1Sho (more )
Structure Level Pattern Image Note
TS21: testis Present S2B Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory