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Gene Expression Data
Assay Details
Assay
Reference: J:138379 Gu S, et al., Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
Assay type: RNA in situ
MGI Accession ID: MGI:6434474
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh probe26
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 6G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mandible condylar condensation Present 6G
TS21: Meckel's cartilage Absent 6G
Specimen 6H: embryonic day 13.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: mandible condylar condensation Weak 6H Significantly down-regulated expression in condylar condensation.
TS21: Meckel's cartilage Absent 6H
Specimen 7E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Present 7E
TS23: mandibular fossa Absent 7E No expression in glenoid fossa.
TS23: Meckel's cartilage Absent 7E
Specimen 7F: embryonic day 15.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: mandible condylar process Weak 7F Expression remains st reduced level in condyle.
TS23: mandibular fossa Present Regionally restricted 7F Ectopic expression in glenoid fossa.
TS23: Meckel's cartilage Absent 7F
Specimen 7G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Weak 7G Reduced expression in condyle.
TS24: mandibular fossa Absent 7G No expression in glenoid fossa.
TS24: Meckel's cartilage Absent 7G
Specimen 7H: embryonic day 16.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: mandible condylar process Strong 7H Increased expression in condyle.
TS24: mandibular fossa Present Regionally restricted 7H Ectopic expression in glenoid fossa.
Specimen E17.5 mutant not shown: embryonic day 17.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: mandibular fossa Present Regionally restricted Ectopic expression in glenoid fossa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory