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Gene Expression Data
Assay Details
Assay
Reference: J:287334 Wunnemann F, et al., Loss of ADAMTS19 causes progressive non-syndromic heart valve disease. Nat Genet. 2020 Jan;52(1):40-47
Assay type: RNA in situ
MGI Accession ID: MGI:6437241
Gene symbol: Adamts19
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 19
Probe: Mm-Adamts19 (500981)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay; an opal dye was used. The authors provided no catalog id for the probe, but this is the only one sold by Advanced Cell Diagnostics for this mouse gene.
Results
Specimen S12A: embryonic day 12.5 (more )
Note: Double labeled: green - Adamts19; red - Lef1 (assay MGI:6437244)
Structure Level Pattern Image Note
TS20: outflow tract endocardial cushion Weak S12G' , S12G , S12A' , S12A
Specimen S12B: embryonic day 14.5 (more )
Note: Double labeled: green - Adamts19; red - Lef1 (assay MGI:6437244)
Structure Level Pattern Image Note
TS22: aortic valve Strong Regionally restricted S12H , S12B' , S12B , S12H' Expression is seen in the interstitial/mesenchymal cells of the valve.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory