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Gene Expression Data
Assay Details
Assay
Reference: J:204460 Nie X, et al., Pkd1 is required for male reproductive tract development. Mech Dev. 2013 Nov-Dec;130(11-12):567-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441880
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67 (AB9260)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3E: embryonic day 16.5; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS24: nephric duct Present 3E Expression in efferent duct.
Specimen 3F: embryonic day 16.5; Pkd1tm1Ggg/Pkd1tm1Ggg (more )
Structure Level Pattern Image Note
TS24: nephric duct Strong 3F Proliferation rate significantly increased in mutant compared to control.
Specimen 3G: embryonic day 16.5; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS24: nephric duct Present 3G Expression in efferent duct.
Specimen 3H: embryonic day 16.5; Pkd1tm1Ggg/Pkd1tm1Ggg (more )
Structure Level Pattern Image Note
TS24: nephric duct Strong 3H Proliferation rate significantly increased in mutant compared to control.
Specimen 4E: embryonic day 16.5; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS24: epithelium of epididymis Present 4E
Specimen 4F: embryonic day 16.5; Pkd1tm1Ggg/Pkd1tm1Ggg (more )
Structure Level Pattern Image Note
TS24: epithelium of epididymis Weak 4F Proliferation rate significantly decreased in epithelium of mutant compare to control.
Specimen 5K: postnatal day 1; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Present 5K
Specimen 5L: postnatal day 1; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: efferent duct of seminal vesicle Present 5L Cell proliferation rate in epithelium of dilated efferent duct comparable to control.
Specimen 6C: embryonic day 18.5; Pkd1tm1Ggg/Pkd1+ (more )
Structure Level Pattern Image Note
TS26: epididymis Present 6C
Specimen 6D: embryonic day 18.5; Pkd1tm1Ggg/Pkd1tm2Ggg, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: epididymis Present Regionally restricted 6D Proliferation in mesenchyme present.
TS26: epithelium of epididymis Weak 6D Low proliferation rate in mutant epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory