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Gene Expression Data
Assay Details
Assay
Reference: J:231312 Baardman ME, et al., Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development. Dis Model Mech. 2016 Apr 1;9(4):413-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6444454
Gene symbol: Myl7
Gene name: myosin, light polypeptide 7, regulatory
Antibody: anti-MLC-2a
Results
Specimen 1A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: left atrium Present 1A
TS23: right atrium Present 1A
TS23: heart right ventricle Present 1A Both the ascending aorta and pulmonary trunk were present.
Specimen 1B: embryonic day 15.5; Lrp2tm1Her/Lrp2tm1Her (more )
Structure Level Pattern Image Note
TS23: heart atrium Present 1B
TS23: heart right ventricle Present 1B Only one outflow vessel, a common arterial trunk above the right ventricle.
Specimen 1C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: heart atrium Present 1C
TS23: heart left ventricle Present 1C
TS23: heart right ventricle Present 1C
TS23: interventricular septum Present 1C
Specimen 1D: embryonic day 15.5; Lrp2tm1Her/Lrp2tm1Her (more )
Structure Level Pattern Image Note
TS23: heart atrium Present 1D
TS23: heart left ventricle Present 1D
TS23: heart right ventricle Present 1D
TS23: interventricular septum Present 1D There was a mild malalignment between the atrial septum and the ventricular septum. The tricuspid valve overrided the inlet ventricular septal defect and was positioned for its major part above the left ventricle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory