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Gene Expression Data
Assay Details
Assay
Reference: J:219234 Wang J, et al., FGF signaling is required for anterior but not posterior specification of the murine liver bud. Dev Dyn. 2015 Mar;244(3):431-43
Assay type: RNA in situ
MGI Accession ID: MGI:6446878
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Probe: flg probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1K: embryonic day 8.0 (more )
Note: 3-4 somite stage embryo, prior to liver bud induction
Structure Level Pattern Image Note
TS12: gut endoderm Present Regionally restricted 1K Expression is seen in the prehepatic endoderm.
TS12: splanchnopleure Present 1K Expression is seen in the mesoderm adjacent to the prehepatic domain.
Specimen 1L: embryonic day 8.0 (more )
Note: 5-6 somite stage embryo, prior to liver bud induction
Structure Level Pattern Image Note
TS12: gut endoderm Present Regionally restricted 1L Expression is seen in the prehepatic endoderm.
TS12: splanchnopleure Present 1L Expression is seen in the mesoderm adjacent to the prehepatic domain.
Specimen 1M: embryonic day 8.0 (more )
Note: 7-8 somite stage embryo, liver bud induction initiated
Structure Level Pattern Image Note
TS12: foregut diverticulum Present Regionally restricted 1M Expression is seen in the prehepatic endoderm.
TS12: splanchnopleure Present 1M Expression is seen in the mesoderm adjacent to the prehepatic domain.
Specimen 1N: embryonic day 8.5 (more )
Note: 9-11 somite stage embryo, anterior liver bud formed
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Regionally restricted 1N Expression is seen in the liver bud.
TS13: splanchnopleure Present 1N Expression is seen in the mesoderm adjacent to the ehepatic domain.
TS13: septum transversum Present 1N
Specimen 1O: embryonic day 9.0 (more )
Note: 12-13 somite stage embryo, posterior liver bud formed
Structure Level Pattern Image Note
TS14: hepatic primordium Present 1O Expression is seen in the liver bud.
TS14: trunk mesenchyme Present Regionally restricted 1O Expression is seen in the mesoderm adjacent to the hepatic domain.
TS14: septum transversum Present 1O
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
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