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Gene Expression Data
Assay Details
Assay
Reference: J:219234 Wang J, et al., FGF signaling is required for anterior but not posterior specification of the murine liver bud. Dev Dyn. 2015 Mar;244(3):431-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6448100
Gene symbol: Mapk3
Gene name: mitogen-activated protein kinase 3
Antibody: anti-pERK
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody used in this assay recognizes the phosphorylated form of the protein.
Results
Specimen 1Z: embryonic day 8.0 (more )
Note: 4 somite stage embryo, prior to liver bud induction
Structure Level Pattern Image Note
TS12: splanchnopleure Present 1Z Prior to hepatic induction, expression is exclusive to the mesoderm adjacent to the prospective hepatic endoderm.
Specimen 1AA: embryonic day 8.0 (more )
Note: 8 somite stage embryo, liver bud induction initiated
Structure Level Pattern Image Note
TS12: foregut diverticulum Present Regionally restricted 1AA Expression is seen throughout the prospective hepatic endoderm.
TS12: splanchnopleure Present 1AA Expression is seen in the mesoderm adjacent to the prospective hepatic endoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
MGI 6.24 		The Jackson Laboratory