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Gene Expression Data
Assay Details
Assay
Reference: J:127471 Wang S, et al., Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech Dev. 2007 Nov-Dec;124(11-12):898-910
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6449807
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-Pdx1
Results
Specimen 1A1 inset: embryonic day 8.5 (more )
Note: Triple labeled: blue - Pdx1; red - Myt1 (assay MGI:6449800); green - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS13: foregut-midgut junction Absent 1A1 inset Expresssion in prospective pancreatic epithelium.
Specimen 1A1: embryonic day 9.0 (more )
Note: Triple labeled: blue - Pdx1; red - Myt1 (assay MGI:6449800); green - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS14: foregut-midgut junction Present Regionally restricted 1A1 Expression in prospective pancreas.
Specimen 1A2: embryonic day 10.5 (more )
Note: Triple labeled: blue - Pdx1; red - Myt1 (assay MGI:6449800); green - Ins1 (assay MGI:6449808) and Ins2 (assay MGI:6450025).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1A2 Expression in prospective pancreas.
Specimen 1B1: embryonic day 9.0 (more )
Note: Triple labeled: blue - Pdx1; red - Myt1 (assay MGI:6449800); green - Gcg (assay MGI:6449809).
Structure Level Pattern Image Note
TS14: foregut-midgut junction Present Regionally restricted 1B1 Expression in prospective pancreas.
Specimen 1B2: embryonic day 10.5 (more )
Note: Triple labeled: blue - Pdx1; red - Myt1 (assay MGI:6449800); green - Gcg (assay MGI:6449809).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1B2 Expression in prospective pancreas.
Specimen S4 E10.5 +/+: embryonic day 10.5 (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 +/+
Specimen S4 E10.5 +/-: embryonic day 10.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 +/-
Specimen S4 E10.5 -/-: embryonic day 10.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS17: pancreas primordium Present S4A E10.5 -/-
Specimen S4 E13.5 +/+: embryonic day 13.5 (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 +/+
Specimen S4 E13.5 +/-: embryonic day 13.5; Myt1tm1.1Ggu/Myt1+ (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 +/-
Specimen S4 E13.5 -/-: embryonic day 13.5; Myt1tm1.1Ggu/Myt1tm1.1Ggu (more )
Note: Double labeled: red - Pdx1; green - Neurog3 (assay MGI:6449812).
Structure Level Pattern Image Note
TS21: pancreas Present S4A E13.5 -/-
Specimen S5D inset: embryonic day 18.5; Myt1tm1Ggu/Myt1tm1.1Ggu, Tg(Pdx1-cre)89.1Dam/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: pancreas Ambiguous S5D inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory