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Gene Expression Data
Assay Details
Assay
Reference: J:182781 Landsman L, et al., Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol. 2011 Sep;9(9):e1001143
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451456
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: Anti-E-Cadherin (610181; Clone 36)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Embryos were fixed in Z-fix (Anatech).
Results
Specimen 1A: embryonic day 9.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nkx3-2tm1(cre)Wez/Nkx3-2+ (more )
Note: Conditional mutant. Triple labeled: blue - Cdh1; red - Pdx1 (assay MGI:6451455); green - Cre reporter.
Structure Level Pattern Image Note
TS15: pancreas primordium Present Regionally restricted 1A Expression is seen in the epithelium.
Specimen 1D: postnatal day 0; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nkx3-2tm1(cre)Wez/Nkx3-2+ (more )
Note: Conditional mutant. Double labeled: red - Cdh1; green - Cre reporter.
Structure Level Pattern Image Note
TS27: pancreas Present Regionally restricted 1D Expression is seen in the epithelium.
Specimen 2B: embryonic day 10.5 (more )
Note: Double labeled: red - Cdh1; green - Pdx1 (assay MGI:6451455).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted 2B Expression is seen in the epithelium.
Specimen 7M: embryonic day 13.5 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS21: pancreas epithelium Present 7M
Specimen 7N: embryonic day 13.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Nkx3-2tm1(cre)Wez/Nkx3-2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: pancreas epithelium Present 7N Mesenchymal tissue is reduced/has been ablated in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
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