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Gene Expression Data
Assay Details
Assay
Reference: J:111788 Kiyozumi D, et al., Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6454315
Gene symbol: Fras1
Gene name: Fraser extracellular matrix complex subunit 1
Antibody: Anti-Fras1
Detection system: Alexa Fluor 488
Results
Specimen 2E my/+ left: embryonic day 13.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS21: back skin Present 2E my/+ left
Specimen 2E my/my left: embryonic day 13.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS21: back skin Weak 2E my/my left Expression considerably reduced in my/my embryos.
Specimen 2F my/+ left: embryonic day 17.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS25: back skin Present 2F my/+ left
Specimen 2F my/my left: embryonic day 17.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS25: back skin Weak 2F my/my left Expression considerably reduced in my/my embryos.
Specimen 2G my/+ left: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: back skin Present 2G my/+ left
Specimen 2G my/my left: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: back skin Weak 2G my/my left Expression considerably reduced in my/my embryos.
Specimen 3C eb/+ left: embryonic day 14.5; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS22: back skin Present 3C eb/+ left
Specimen 3C eb/eb left: embryonic day 14.5; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS22: back skin Trace 3C eb/eb left Expression almost absent in eb/eb embryos.
Specimen 3D eb/+ left: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: back skin Present 3D eb/+ left
Specimen 3D eb/eb left: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: back skin Trace 3D eb/eb left Expression almost absent in eb/eb embryos.
Specimen 5J +/- left: embryonic day 14.5; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS22: back skin Present 5J +/- left
Specimen 5J -/- left: embryonic day 14.5; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS22: back skin Weak 5J -/- left Expression reduced in comparison to heterozygotes.
Specimen 5K +/- left: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: back skin Present 5K +/- left
Specimen 5K -/- left: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: back skin Weak 5K -/- left Expression reduced in comparison to heterozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory