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Gene Expression Data
Assay Details
Assay
Reference: J:229890 Ang SY, et al., KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation. Development. 2016 Mar 1;143(5):810-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6456792
Gene symbol: Kmt2d
Gene name: lysine (K)-specific methyltransferase 2D
Results
Specimen S1A E9.5: embryonic day 9.5 (more )
Note: Triple labeled: green - Kmt2d; red - Tpm1 (assay MGI:6456793); blue - DAPI.
Structure Level Pattern Image Note
TS15: heart Present Ubiquitous S1A 9.5
Specimen S1A E10.5: embryonic day 10.5 (more )
Note: Triple labeled: green - Kmt2d; red - Tpm1 (assay MGI:6456793); blue - DAPI.
Structure Level Pattern Image Note
TS17: heart Present Ubiquitous S1A 10.5
Specimen S1A E11.5: embryonic day 11.5 (more )
Note: Triple labeled: green - Kmt2d; red - Tpm1 (assay MGI:6456793); blue - DAPI.
Structure Level Pattern Image Note
TS19: heart Present Ubiquitous S1A 11.5
Specimen S1A E12.5: embryonic day 12.5 (more )
Note: Triple labeled: green - Kmt2d; red - Tpm1 (assay MGI:6456793); blue - DAPI.
Structure Level Pattern Image Note
TS20: heart Present Ubiquitous S1A 12.5
Specimen 1A: embryonic day 12.5 (more )
Note: Triple labeled: green - Kmt2d; red - Tpm1 (assay MGI:6456793); blue - DAPI.
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present Regionally restricted 1A Expression in nuclei of myocardial cells.
Specimen 1B: embryonic day 12.5 (more )
Note: Triple labeled: green - Kmt2d; red - Pecam1 (assay MGI:6456794); blue - DAPI.
Structure Level Pattern Image Note
TS20: endocardial lining Present Regionally restricted 1B Expression in nuclei of endocardial cells.
Specimen S2E fl/+; mTmG/+: embryonic day 12.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Kmt2dtm1.1Kaig/Kmt2d+, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Triple labeled: red - Kmt2d; green - Cre reporter; blue - DAPI.
Structure Level Pattern Image Note
TS20: interventricular septum Present S2E (left)
Specimen S2E fl/fl; mTmG/+: embryonic day 12.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Triple labeled: red - Kmt2d; green - Cre reporter; blue - DAPI.
Structure Level Pattern Image Note
TS20: interventricular septum Weak Regionally restricted S2E (right) Loss of expression in GFP-expressing cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/22/2024
MGI 6.24 		The Jackson Laboratory