Sftpc Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:265020 Tang X, et al., EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. J Clin Invest. 2017 Dec 1;127(12):4314-4325
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6456989
Gene symbol:	Sftpc
Gene name:	surfactant associated protein C

Antibody:

Results

3C merge ©

3C mSP-C ©

Specimen 3C: embryonic day 18.5 (more

)
Note: Double labeled: red - mSP-C (Sftpc); green - proSP-C (Sftpc assay MGI:6456988).

Structure	Level	Pattern	Image	Note
TS26: lung	Present		3C mSP-C , 3C merge

3D merge ©

3D mSP-C ©

Specimen 3D: embryonic day 18.5; Emc3^{tm1c(EUCOMM)Wtsi}/Emc3^{tm1c(EUCOMM)Wtsi}, Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ (more

)
Note: Conditional mutant. Double labeled: red - mSP-C (Sftpc); green - proSP-C (Sftpc assay MGI:6456988).

Structure	Level	Pattern	Image	Note
TS26: lung alveolus	Present	Regionally restricted	3D merge , 3D mSP-C	Expression accumulated in cytoplasm of alveolar type 2 (AT2) cells, abnormally colocalized with proSPC and was not secreted from cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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