Ins2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:155058 Zhang H, et al., Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev. 2009 Dec;126(11-12):958-73
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6458841
Gene symbol:	Ins2
Gene name:	insulin II

Antibody:

anti-insulin

Results

2C ©

Specimen 2C: embryonic day 15.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Ins1 and Ins2; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS23: endocrine pancreas	Present	Regionally restricted	2C

2F ©

Specimen 2F: postnatal day 1; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Ins1 and Ins2; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present	Regionally restricted	2F

Specimen E18.5: embryonic day 18.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: endocrine pancreas	Weak	Regionally restricted		Number of beta cells was reduced at E18.5.

S2A* ©

Specimen S2A*: postnatal day 2; Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present		S2A*

S2B* ©

Specimen S2B*: postnatal day 2; Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺, Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present		S2B*

6D ©

Specimen 6D: postnatal adult; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: green - Ins1 and Ins2; red - cytokeratin.

Structure	Level	Pattern	Image	Note
TS28: endocrine pancreas	Present		6D

6E ©

Specimen 6E: postnatal adult; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - cytokeratin.

Structure	Level	Pattern	Image	Note
TS28: pancreas	Present	Regionally restricted	6E	Expressing cells abnormally located within multilayered epithelium.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/17/2024 MGI 6.24