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Gene Expression Data
Assay Details
Assay
Reference: J:297161 Javali A, et al., Modulation of beta-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch. Dev Dyn. 2020 May 19;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505459
Gene symbol: Cdh2
Gene name: cadherin 2
Results
Specimen 3De: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: trigeminal preganglion Strong 3De Abundant expression in proximal region cranial crest cells (CNCC) forming anlage ot trigeminal ganglion.
Specimen 3Df: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Weak Regionally restricted 3Df Reduced expression in distal region (skeletogenic CNCC compartment) of first pharyngeal arch.
Specimen not shown: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Present Graded
Specimen 6C: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Weak Regionally restricted 6C (left) , 6C (right) Expression reduced in distal region (cells in first pharyngeal arch).
Specimen 6D (left): embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Present 6D (left) Expression not reduced in distal cranial neural crest cells (CNCC) compared to proximal domain. Authors report uniform expression levels along dorso-ventral axis.
Specimen 6Ea: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Regionally restricted 6Ea
Specimen 6Eb: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Weak Regionally restricted 6Eb Expression reduced in distal region (cells in first pharyngeal arch).
Specimen 6Ec: embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Cdh2; white - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 6Ec (left) Expression not reduced in distal cranial neural crest cells (CNCC) compared to proximal domain. Authors report uniform expression levels along dorso-ventral axis.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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