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Gene Expression Data
Assay Details
Assay
Reference: J:297161 Javali A, et al., Modulation of beta-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch. Dev Dyn. 2020 May 19;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505464
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Results
Specimen 7A (left): embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 7A (left)
TS15: head mesenchyme Present 7A (left) Expression in cranial mesoderm.
Specimen 7Aa: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 7Aa
Specimen 7A (right): embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Regionally restricted 7A (right) Expression in residual cranial neural crest cells (CNCC) in hypoplastic first pharyngeal arch.
Specimen 7Ab: embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Regionally restricted 7Ab Expression in residual cranial neural crest cells (CNCC) in hypoplastic first pharyngeal arch.
Specimen 7B Twist1 inset: embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0 (more )
Note: Conditional mutant. Double labeled: green - Twist1; red - Ctnnb1 (assay MGI:6505463).
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Present Regionally restricted 7B (right) , 7B (center left) Expression in residual cranial neural crest cells (CNCC) in hypoplastic first pharyngeal arch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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