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Gene Expression Data
Assay Details
Assay
Reference: J:300507 Gao P, et al., Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes Dev. 2020 Jul 1;34(13-14):950-964
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511249
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Antibody: anti-RUNX1/AML1 + RUNX2 + RUNX3 (EPR3099; ab92336)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 7A +/+: embryonic day 10.5 (more )
Note: Triple labeled: teal - Runx1; white - Kit (assay MGI:6511250); magenta - Pecam1 (CD31; assay MGI:6511248)
Structure Level Pattern Image Note
TS17: hematopoietic system Present Clusters 7Aii +/+ , 7Ai +/+ Expression is seen in hemogenic endothelial cells.
Specimen 7A -/-: embryonic day 10.5; Sp3tm1Sus/Sp3tm1Sus (more )
Note: Triple labeled: teal - Runx1; white - Kit (assay MGI:6511250); magenta - Pecam1 (CD31; assay MGI:6511248)
Structure Level Pattern Image Note
TS17: hematopoietic system Present Clusters 7Ai -/- , 7Aii -/- Expression is seen in hemogenic endothelial cells; their numbers are reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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