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Gene Expression Data
Assay Details
Assay
Reference: J:280280 Rutledge EA, et al., Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6512008
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 (EPR14335; ab185230)
Detection system: Secondary antibody
Results
Specimen 5C: embryonic day 12.5 (more )
Note: Double labeled: red - Sox9; blue - pan-cytokeratin immunostaining.
Structure Level Pattern Image Note
TS20: lung epithelium Present Single cells 5C Expression is present in distal epithelial progenitor cells.

Specimen 5D: embryonic day 12.5; Adamts18tm1(KOMP)Vlcg/Adamts18tm1(KOMP)Vlcg (more )
Note: Double labeled: red - Sox9; blue - pan-cytokeratin immunostaining.
Structure Level Pattern Image Note
TS20: lung epithelium Present Single cells 5D Expression is present in distal epithelial progenitor cells; no discernable difference was observed between mutant and wild type.

Specimen 9C: embryonic day 12.5 (more )
Note: 51-52 somite-stage embryo. Dividing cells labeled with Edu; section stained with Hoechst.
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 9C Expression is present in tip cells.

Specimen 9D: embryonic day 12.5; Adamts18tm1(KOMP)Vlcg/Adamts18tm1(KOMP)Vlcg (more )
Note: 51-52 somite-stage embryo. Dividing cells labeled with Edu; section stained with Hoechst.
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 9D Expression is present in tip cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory